Test Code HDVQU Hepatitis D Virus RNA Detection and Quantification, Real-Time RT-PCR, Serum
Ordering Guidance
This test should be requested for all individuals who are newly confirmed to be positive for hepatitis B virus surface antigen (HBsAg) or HDV total antibodies in serum.
Shipping Instructions
1. Freeze serum immediately, and ship specimen frozen on dry ice.
2. If shipment will be delayed for more 24 hours, freeze serum at -20 to -80° C (up to 35 days) until shipment on dry ice.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 2.2 mL
Collection Instructions:
1. Centrifuge blood collection tube per collection tube manufacturer's instructions (eg, centrifuge within 2 hours of collection for BD Vacutainer tubes).
2. Aliquot serum into plastic vial.
Useful For
Detection of hepatitis D virus (HDV) for diagnosis of acute or chronic hepatitis D
Determine HDV RNA level in serum to monitor progression and response to antiviral therapy for chronic hepatitis D
Testing Algorithm
For more information see Hepatitis D: Diagnostic Testing Algorithm.
Method Name
Real-Time, Reverse Transcription-Polymerase Chain Reaction (RT-PCR)
Reporting Name
HDV RNA Detect / Quant, SSpecimen Type
Serum SSTSpecimen Minimum Volume
1.0 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum SST | Frozen (preferred) | 35 days | ALIQUOT TUBE |
Refrigerated | 5 days | ALIQUOT TUBE |
Reference Values
Undetected
Day(s) Performed
Varies (once per week)
Report Available
1 to 10 daysPerforming Laboratory

Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
87523
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
HDVQU | HDV RNA Detect / Quant, S | 85512-2 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
621375 | HDV RNA Detect / Quant, S | 85512-2 |