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Test Code LAMO Lamotrigine, Serum


Specimen Required


Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Draw blood immediately before next scheduled dose.

2. For sustained-release formulations ONLY, draw blood a minimum of 12 hours after last dose.

3. Spin down within 2 hours of draw.

4. Remove serum from serum gel tube if applicable.


Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Neurology Specialty Testing Client Test Request (T732)

-General Request (T239)

Useful For

Monitoring serum concentration of lamotrigine

 

Assessing compliance

 

Adjusting lamotrigine dose in patients receiving other anticonvulsant drugs which interact pharmacokinetically with lamotrigine

Method Name

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Lamotrigine, S

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

Patients receiving therapeutic doses usually have lamotrigine concentrations of 2.5-15.0 mcg/mL.

Day(s) and Time(s) Performed

Monday through Friday; Continuous until 2 p.m.

Saturday; Continuous until 1 p.m.

Sunday; 11 a.m.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

80175

LOINC Code Information

Test ID Test Order Name Order LOINC Value
LAMO Lamotrigine, S 6948-4

 

Result ID Test Result Name Result LOINC Value
80999 Lamotrigine, S 6948-4