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Test Code NSAI Neurosyphilis IgG, Antibody Index, Spinal Fluid


Specimen Required


Only orderable as part of a profile. For more information see NSAIP / Neurosyphilis IgG Antibody Index with VDRL, Serum and Spinal Fluid.

 

Both spinal fluid (CSF) and serum are required for this test. CSF and serum must be collected within a maximum of 24 hours of each other.

 

Specimen Type: Spinal fluid

Container/Tube: Sterile vial

Specimen Volume: 2.2 mL

Collection Instructions:

1. The spinal fluid (CSF) specimen must be collected within 24 hours of the serum specimen, preferably at the same time.

2. The CSF aliquot should be from the second, third, or fourth CSF vial collected during the lumbar puncture. Do not submit CSF from the first vial due to the possibility of blood contamination, which will cause specimen rejection.

3. Label vial as spinal fluid or CSF.

4. Band CSF specimen together with the serum sample.

 

Specimen Type: Serum

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2.2 mL

Collection Instructions:

1. Within 24 hours of collection of the spinal fluid specimen, a serum specimen must also be collected, preferably at the same time.

2. Centrifuge and aliquot serum into a plastic vial.

3. Label tube as serum.

4. Band serum specimen together with the CSF sample.


Useful For

Aid in the diagnosis of neuroinvasive syphilis as part of a profile

Method Name

Only orderable as part of a profile. For more information see NSAIP / Neurosyphilis IgG Antibody Index with VDRL, Serum and Spinal Fluid.

 

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Neurosyphilis IgG, Ab Index

Specimen Type

CSF

Specimen Minimum Volume

Spinal fluid: 1.5 mL; Serum: 1.5 mL

Specimen Stability Information

Specimen Type Temperature Time
CSF Refrigerated (preferred) 10 days
  Frozen  10 days

Reference Values

Only orderable as part of a profile. For more information see NSAIP / Neurosyphilis IgG Antibody Index with VDRL, Serum and Spinal Fluid.

 

Antibody Index: 0.6-1.2

 

Reference values apply to all ages.

Day(s) Performed

Monday through Friday

Report Available

2 to 4 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82784 x 2

82040

86780 x 2

82042

LOINC Code Information

Test ID Test Order Name Order LOINC Value
NSAI Neurosyphilis IgG, Ab Index 105193-7

 

Result ID Test Result Name Result LOINC Value
NSY3 Neurosyphilis IgG Ab Index Value 105193-7
NSY4 Neurosyphilis IgG Ab Index Interp 69048-7