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Test Code SGSU Synthetic Glucocorticoid Screen, Random, Urine


Ordering Guidance


 



Specimen Required


Supplies: Urine tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube

Specimen Volume: 5 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.


Useful For

Confirming the presence of listed synthetic glucocorticoids in urine specimens (see Interpretation)

 

Confirming the cause of glucocorticoid-induced adrenal insufficiency

 

This test is not useful for detection of fluticasone propionate.

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Reporting Name

Synthetic Glucocorticoid Screen, U

Specimen Type

Urine

Specimen Minimum Volume

0.6 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Frozen 14 days

Reference Values

Negative

Cutoff concentrations

Betamethasone: 0.10 mcg/dL

Budesonide: 0.20 mcg/dL

Dexamethasone: 0.10 mcg/dL

Fludrocortisone: 0.10 mcg/dL

Megestrol acetate: 0.10 mcg/dL

Methylprednisolone: 0.10 mcg/dL

Prednisolone: 0.10 mcg/dL

Prednisone: 0.10 mcg/dL

Triamcinolone acetonide: 0.10 mcg/dL

 

Values for normal patients not taking these synthetic glucocorticoids should be less than the cutoff concentration (detection limit).

Day(s) Performed

Wednesday

Report Available

5 to 14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80299

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SGSU Synthetic Glucocorticoid Screen, U 46959-3

 

Result ID Test Result Name Result LOINC Value
23562 Betamethasone 46946-0
23563 Budesonide 46947-8
23564 Dexamethasone 46948-6
23565 Fludrocortisone 46949-4
23569 Megestrol Acetate 46953-6
23570 Methylprednisolone 46954-4
23571 Prednisolone 46955-1
23572 Prednisone 46956-9
23574 Triamcinolone Acetonide 46958-5