Test Code SUPRA Supersaturation Profile, Random, Urine
Ordering Guidance
A timed 24-hour urine collection is the preferred specimen for measuring and interpreting this profile to determine kidney stone risk factors (SUP24 / Supersaturation Profile, 24 Hour, Urine). Random urine collections with individual analytes normalized to urinary creatinine may be of some clinical use in patients who cannot collect a 24-hour specimen, typically small children. Therefore, this test is offered on random collections for children less than 16 years old.
X-ray dyes and contrast media will affect uric acid test results.
-If a kidney X-ray with dye or computerized tomography (CT) scan with contrast has been performed, patient should wait a minimum of 1 day before starting collection.
-If a cholangiography (bile duct X-ray) has performed, patient should wait 7 days before starting collection.
-Urine must be collected before tablets have been taken for gallbladder X-ray, otherwise patient should wait 7 days before starting collection.
Necessary Information
Patient's age is required.
Specimen Required
Supplies:
-Urine Tubes, 10 mL (T068)
-Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: 90 mL urine container
Submission Container/Tube: 2 x 10 mL plastic urine tubes and 5 x 5 mL plastic urine tubes
Specimen Volume: 40 mL
Collection Instructions:
1. Collect a random urine specimen, mix collection container thoroughly and divide the urine into 7 plastic tubes (2 x 10 mL and 5 x 5 mL).
2. Refrigerate specimen after collection. Specimen pH should be between 4.5 and 8 and will stay in this range if kept refrigerated. Specimens with pH above 8 indicate bacterial contamination, and testing will be canceled. Do not attempt to adjust pH as it will adversely affect results.
Useful For
Diagnosis and management of patients with renal lithiasis:
-Predicting the likely composition of the stone, in patients who have a radiopaque stone, for whom stone analysis is not available which may help in designing a treatment program
-Identifying specific risk factors for stones formation using a random urine collection
-Monitoring the effectiveness of therapy by confirming that the crystallization potential has indeed decreased
-Evaluation of kidney excretion of acid and urine pH
Profile Information
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
SRINT | Supersaturation, Random, U 1 | No | Yes |
RANAU | Sodium, Random, U | Yes, (order RNAUR) | Yes |
RAKUR | Potassium, Random, U | Yes, (order RKUR) | Yes |
RACAL | Calcium, Random, U | Yes, (order CACR3) | Yes |
RAMAG | Magnesium, Random, U | Yes, (order MAGRU) | Yes |
RACLU | Chloride, Random, U | Yes, (order RCHLU) | Yes |
RAPOU | Phosphorus, Random, U | Yes, (order RPHOC) | Yes |
RASUL | Sulfate, Random, U | No | Yes |
RACIT | Citrate Excretion, Random, U | Yes, (order CITRA) | Yes |
RAOXU | Oxalate, Random, U | Yes, (order ROXUR) | Yes |
RAPHU | pH, Random, U | No | Yes |
RAURA | Uric Acid, Random, U | Yes, (order RURC1) | Yes |
RACTU | Creatinine, Random, U | Yes, (order RCTUR) | Yes |
RAOSM | Osmolality, Random, U | No | Yes |
RAAMM | Ammonium, Random, U | Yes, (order RAMBO) | Yes |
Method Name
RACIT, RAAMM, RAOXU: Enzymatic
RAOSM: Freezing Point Depression
RASUL: High-Performance Ion Chromatography (HPIC)
RAMAG: Colorimetric Endpoint Assay
RACAL, RAPOU: Photometric
RAPHU: pH Meter
RANAU, RAKUR, RACLU: Potentiometric, Indirect Ion-Selective Electrode (ISE)
RACTU: Enzymatic Colorimetric Assay
RAURA: Uricase
Reporting Name
Supersaturation, Random, USpecimen Type
UrineSpecimen Minimum Volume
30 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Urine | Refrigerated (preferred) | 14 days | |
Frozen | 14 days | ||
Ambient | 72 hours |
Reference Values
The following analytes do not have any established reference values:
Sodium, potassium, chloride, phosphorus, citrate, sulfate, and oxalate
pH: 4.5-8.0
CREATININE
≥18 years old: 16-326 mg/dL
Reference values have not been established for patients who are younger than 18 years.
OSMOLALITY
0-11 months: 50-750 mOsm/kg
≥12 months: 150-1,150 mOsm/kg
AMMONIUM
18-77 years: 3-65 mmol/L
No reference values established for patients who are younger than 18 years or older than 77 years.
CALCIUM
1 month-<12 months: 0.03-0.81 mg/mg creat
12 months-<24 months: 0.03-0.56 mg/mg creat
24 months-<3 years: 0.02-0.50 mg/mg creat
3 years-<5 years: 0.02-0.41 mg/mg creat
5 years-<7 years: 0.01-0.30 mg/mg creat
7 years-<10 years: 0.01-0.25 mg/mg creat
10 years-<18 years: 0.01-0.24 mg/mg creat
18 years-83 years: 0.05-0.27 mg/mg creat
Reference values have not been established for patients who are younger than 1 month or older than 83 years.
MAGNESIUM
Magnesium/Creatinine Ratio:
1 month-<12 months: 0.10-0.48 mg/mg creat
12 months-<24 months: 0.09-0.37 mg/mg creat
24 months-<3 years: 0.07-0.34 mg/mg creat
3 years-<5 years: 0.07-0.29 mg/mg creat
5 years-<7 years: 0.06-0.21 mg/mg creat
7 years-<10 years: 0.05-0.18 mg/mg creat
10 years-<14 years: 0.05-0.15 mg/mg creat
14 years-<18 years: 0.05-0.13 mg/mg creat
18 years-83 years: 0.04-0.12 mg/mg creat
Reference values have not been established for patients who are younger than 1 month or older than 83 years.
Day(s) Performed
Monday through Sunday
Report Available
2 to 5 daysPerforming Laboratory
Mayo Clinic Laboratories in RochesterTest Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82310-Calcium
82436-Chloride
82507-Citrate excretion
82570-Creatinine
83735-Magnesium
83935-Osmolality
83945-Oxalate
83986-pH
84105-Phosphorus
84133-Potassium
84300-Sodium
84392-Sulfate
84560-Uric acid
82140-Ammonium
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
SUPRA | Supersaturation, Random, U | 101929-8 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
RASUC | Sulfate, Random, U | 2975-1 |
RAPHU | pH, Random, U | 2756-5 |
RAOSU | Osmolality, Random, U | 2695-5 |
RANAC | Sodium, Random, U | 2955-3 |
RACTU | Creatinine, Random, U | 2161-8 |
RAKUC | Potassium, Random, U | 2828-2 |
RACLC | Chloride, Random, U | 2078-4 |
RAAMM | Ammonium, Random, U | 1842-4 |
RACAC | Calcium, Random, U | 17862-4 |
CITCO | Citrate Excretion, Random, U | 2128-7 |
RAMGC | Magnesium, Random, U | 19124-7 |
POUCO | Phosphorus, Random, U | 2778-9 |
RAUAC | Uric Acid, Random, U | 3086-6 |
OXMCO | Oxalate, Random, U (mmol/L) | 15086-2 |
616399 | Calcium Oxalate Crystal | In Process |
616400 | Brushite Crystal | In Process |
OXGCO | Oxalate, Random, U (mg/L) | 2700-3 |
UACCR | Uric Acid/Creat Ratio, Random, U | 3089-0 |
PHOCR | Phosphorus/Creat Ratio, Random, U | 11141-9 |
MAGCR | Magnesium/Creat Ratio, Random, U | 13474-2 |
CITCR | Citrate/Creatinine Ratio, Random, U | 13722-4 |
CALCR | Calcium/Creatinine Ratio, Random, U | 9321-1 |
OXUCR | Oxalate/Creatinine Ratio, Random, U | 13483-3 |
616401 | Hydroxyapatite Crystal | In Process |
616402 | Uric Acid Crystal | In Process |
31246 | Interpretation | 69051-1 |
Forms
If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.