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Test Code VANC Tr Vancomycin, Trough

Important Note

Pharmacokinetic factors influence the correct time of sample collection after the last dose. These factors include dosage form, mode of administration, concomitant drug therapy, and biological variations affecting drug dispositions.

Performing Laboratory

Memorial Hospital Laboratory- Automated Procedures  304-388-5953       
General Hospital Laboratory 304-388-6244
Women and Children's Hospital Laboratory 304-388-2385
Teays Valley Hospital Laboratory 304-757-1770
Plateau Medical Center Laboratory 304-469-8621
Greenbrier Valley Laboratory 304-647-6060

Collection and Processing

Trough samples should be drawn just before next scheduled dose

Specimen Requirements

Preferred: Plasma-Dark Green Lithium Heparin or Serum- red top

Acceptable: Plasma-Mint Green or Serum-SST gold top

Allow SST or red top to completely clot      

Spin and physically separate plasma/serum from contact with cells as soon as possible

4 mL of plasma/serum (minimum 2 mL)

Specimen Rejection

  • Improperly labeled, collected, stored, and transported
  • Quantity not sufficient
  • Hemolyzed 

Storage and Stability

Specimen is stable for 8 hours at room temperature

If not analyzed within 8 hours, store serum/plasma frozen at <-20oC

Reference Values

Therapeutic Range

Trough 10.0-20.0 mcg/mL

 

Critical Values

Trough > 25.0 mcg/mL

Methodology

Homogeneous enzyme immunoassay  Memorial, General, Women and Children's, Teays, Plateau 
Two-Point Rate Greenbrier 

Days Test Set Up and Turnaround

Monday through Sunday, Continuously

AM Collection Expected by 9AM same day
Routine Expected within 24 hrs
Stat Expected within 1 hr
Timed Expected results are test dependant

CPT Coding

80202