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Test Code VPA Valproic Acid

Important Note

Trough: Collect sample just before next dose.

Peak: Serum Valproic Acid level that best represents the peak tissue level should be drawn 1-3 hours after oral dose is given.

Performing Laboratory

General Hospital Laboratory 304-388-6244
Women and Children's Hospital Laboratory 304-388-2385
Teays Valley Hospital Laboratory 304-757-1770
Greenbrier Valley Laboratory 304-647-6060

Specimen Requirements

Preferred: Plasma-Dark Green Lithium Heparin or Serum- red top

Acceptable: Plasma-Mint Green or Serum-SST gold top

Allow SST or red top to completely clot      

Spin and physically separate plasma/serum from contact with cells as soon as possible

4 mL of plasma/serum (minimum 2 mL)

Specimen Rejection

  • Improperly labeled, collected, stored, and transported
  • Quantity not sufficient

Storage and Stability

Room Temp 8 hours
Refrigerated 2-8oC 48 hours
Frozen <-20oC 1 year

Reference Values

50-100 ug/mL

Critical Value: >149 ug/mL

Methodology

Homogeneous Enzyme Imunoassay General, Women and Children's, Teays
Two-Point Rate Greenbrier 

Days Test Set Up and Turnaround

Monday through Sunday, Continuously 

AM Collection Expected by 9AM same day
Routine Expected within 24 hrs
Stat Expected within 1 hr
Timed Expected results are test dependant

CPT Coding

80164